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2023 NFL picks, score predictions for Week 1

Sayre Bedinger
Sayre Bedinger

NFL Spin Zone

KANSAS CITY, MISSOURI - AUGUST 26: Patrick Mahomes #15 of the Kansas City Chiefs smiles during an on-field television interview during the third quarter of a preseason game against the Cleveland Browns at GEHA Field at Arrowhead Stadium on August 26, 2023 in Kansas City, Missouri. (Photo by David Eulitt/Getty Images)

At long last, the seven months of waiting between the end of the Super Bowl and the start of the new regular season are over. The 2023 NFL season is upon us, which means it’s time for another year of NFL picks and score predictions for every single game.

2023 NFL picks and score predictions for Week 1

NFL Picks
NFL Picks – Mandatory Credit: Jay Biggerstaff-USA TODAY Sports

Detroit Lions (9-8) @ Kansas City Chiefs (14-3)

The reigning Super Bowl champion Kansas City Chiefs begin their title defense at home against the Detroit Lions, a team that experienced a ton of momentum at the end of last season. But that was now almost eight months ago.

NFL Picks
NFL Picks – Mandatory Credit: John Jones-USA TODAY Sports

Carolina Panthers (7-10) at Atlanta Falcons (7-10)

NFL Picks
NFL Picks (Photo by Logan Riely/Getty Images)

Houston Texans (3-13-1) @ Baltimore Ravens (10-7)

NFL Picks
NFL Picks

Cincinnati Bengals (12-4) @ Cleveland Browns (7-10)

NFL Picks
NFL Picks – Mandatory Credit: Melina Myers-USA TODAY Sports

Jacksonville Jaguars (9-8) @ Indianapolis Colts (4-12-1)

NFL Picks
NFL Picks – Mandatory Credit: Jeffrey Becker-USA TODAY Sports

Tampa Bay Buccaneers (8-9) @ Minnesota Vikings (13-4)

NFL Picks
NFL Picks – Mandatory Credit: Andrew Nelles-USA TODAY Sports

Tennessee Titans (7-10) @ New Orleans Saints (7-10)

NFL Picks
NFL Picks – Mandatory Credit: Sergio Estrada-USA TODAY Sports

San Francisco 49ers (13-4) @ Pittsburgh Steelers (9-8)

NFL Picks
NFL Picks – Mandatory Credit: Brad Mills-USA TODAY Sports

Arizona Cardinals (4-13) @ Washington Commanders (8-8-1)

NFL Picks
NFL Picks – Mandatory Credit: Daniel Bartel-USA TODAY Sports

Green Bay Packers (8-9) @ Chicago Bears (3-14)

NFL Picks
NFL Picks – Mandatory Credit: Kyle Terada-USA TODAY Sports

Las Vegas Raiders (6-11) @ Denver Broncos (5-12)

The Sean Payton era begins for the Denver Broncos. The Jimmy Garoppolo era begins for the Las Vegas Raiders.

NFL Picks
NFL Picks – Mandatory Credit: Kirby Lee-USA TODAY Sports

Miami Dolphins (9-8) @ Los Angeles Chargers (10-7)

NFL Picks
NFL Picks – Mandatory Credit: Tommy Gilligan-USA TODAY Sports

Philadelphia Eagles (14-3) @ New England Patriots (8-9)

NFL Picks
NFL Picks – Mandatory Credit: Kirby Lee-USA TODAY Sports

Los Angeles Rams (5-12) @ Seattle Seahawks (9-8)

NFL Picks
NFL Picks – Mandatory Credit: Kirby Lee-USA TODAY Sports

Dallas Cowboys (12-5) @ New York Giants (9-7-1)

NFL Picks
NFL Picks – Mandatory Credit: Ed Mulholland-USA TODAY Sports

Buffalo Bills (13-3) @ New York Jets (7-10)

Sayre Bedinger

Sayre Bedinger

Sayre Bedinger is a site expert for FanSided who has covered the Denver Broncos since 2013. Sayre's Broncos fandom developed after his grandparents relocated to Estes Park, CO during the John Elway glory days, and that passion for the team has resulted in many years and thousands of articles covering the team. Sayre is also the site co-expert of FanSided's NFL Spin Zone, providing coverage of the entire league. He is also a contributor for FanSided's Lombardi Ave (Packers), The Landry Hat (Cowboys), and a number of other local sites covering NFL teams. Sayre was inducted into the FanSided Hall of Fame in 2017. He is also the co-host of the Locked On Broncos Podcast and has been featured as a regular contributor on Bleacher Report. Sayre is a Disney World fanatic who hopes to take his family on trips there multiple times a year.