2025 NFL picks, score predictions for every Week 15 game

Picks and score predictions for every Week 15 game
NFL Picks, NFL Predictions; Drake Maye and Josh Allen
NFL Picks, NFL Predictions; Drake Maye and Josh Allen | Kathryn Riley/GettyImages
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Los Angeles Chargers (9-4) @ Kansas City Chiefs (6-7)

Sunday, December 14, 1:00 PM ET

Who would have thought that we’d be talking about the Kansas City Chiefs trying to get back to .500 in the middle of the month of December?

These are wild times we’re living in right now.

The Chiefs’ dynasty is officially over, even though their 2025 season isn’t. They can obviously still find a way to scrape and claw their way into the postseason, but the loss the Chiefs suffered at home against the Houston Texans mathematically eliminated the possibility of this team winning a 10th-straight AFC West title.

The Chiefs have run the NFL for such a long time, it almost still just doesn’t feel real. They’ll have another chance on their home field to bounce back against a division rival, which would be huge for their hopes of returning to the postseason, at the very least.

Unfortunately for Kansas City’s struggling offense, the Chargers boast one of the top pass defenses in the NFL. 

The Chargers showed some outstanding resilience on Monday night against the Eagles. Even with Justin Herbert just having had surgery on his non-throwing hand, he was still out there making tough throws and even clutch plays as a runner. You have to tip your cap to the way the Chargers played, but are they going to be able to put the final nail in the Chiefs' proverbial coffin on the road?

Despite the way they’ve played this year, the oddsmakers are still favoring the Chiefs by a whopping 4.5 points at home in this one. I think they can squeak by in a close one.

Prediction: Chiefs win 25-23

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