2021 NFL picks, score predictions for Week 7

Photo by Jim McIsaac/Getty Images
Photo by Jim McIsaac/Getty Images /
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NFL Picks Week 7
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Houston Texans (1-5) at Arizona Cardinals (6-0)

Sunday, October 24, 4:25 PM ET

There’s zero chance the Houston Texans win this one, right? They’re easily one of the worst teams in the NFL, being matched up against the only undefeated team remaining. Anything can happen on Sundays, but it seems pretty easy to predict the Arizona Cardinals as the winners here.

We all knew the Texans were going to be bad this season, and they haven’t disappointed. Despite showing flashes early in the season, they’ve followed up their surprising Week 1 win with five straight losses. Now going head-to-head with the 6-0 Cardinals, the odds of that losing streak extending to six games are extremely high.

I’ll give some credit to Davis Mills, who’s held his own despite being thrown to the wolves as a rookie quarterback. But with the Cardinals’ pass rush and opportunistic secondary, chances are high that he has a tough day down in Glendale.

Kyler Murray puts on another dazzling performance, spreading the ball all over the field to his many dangerous weapons. By the start of the fourth quarter, the Cardinals have it in cruise control as they easily earn their seventh win of the 2021 campaign.

Prediction: Cardinals win 37-13 | Spread: Cardinals (-17)