Predicting every NFL Week 1 game of the 2022 season

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Week 1 of the 2022 NFL Season is less than two months away. Let’s break down every game and predict who comes out 1-0 after Week 1!

With NFL training camp around the corner, why not go ahead and predict the entire Week 1 slate of games for the upcoming season?

We always get a nice set of games to break into the season with and this year is no exception. Let’s get right into it with the Thursday Night Football game for Week 1 of the 2022 NFL season.

NFL Week 1

NFL Free Agency: Los Angeles Rams head coach Sean McVay with defensive tackle Aaron Donald (99) and quarterback Matthew Stafford (9) against the Arizona Cardinals at State Farm Stadium. (Mark J. Rebilas-USA TODAY Sports)

Buffalo Bills
Los Angeles Rams
Thursday, Sept 8
8:20 PM ET

NFL Week 1 predictions: Buffalo Bills vs. Los Angeles Rams

The reigning Super Bowl Champion Los Angeles Rams take on the Super Bowl favorite Buffalo Bills for the season opener.

The two juggernauts meet up at the same field where the Rams just secured their Lombardi Trophy, SoFi Stadium in Inglewood.

While the Rams are obviously coming off a fantastic championship victory the Bills have had the heartbreaking loss in the playoffs on their mind all offseason.

The Rams have the playmakers on both sides of the ball but the Bills made sure to beef up their only true weakness; their defense. The Bills come out firing and upset the Rams to start the season 1-0.

Bills 30 Rams 27

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