Predicting every NFL Week 1 game of the 2022 season

Feb 7, 2020; Tampa, FL, USA; General view of the NFL Shield logo on the field before Super Bowl LV between the Tampa Bay Buccaneers and the Kansas City Chiefs at Raymond James Stadium. Mandatory Credit: Kim Klement-USA TODAY Sports
Feb 7, 2020; Tampa, FL, USA; General view of the NFL Shield logo on the field before Super Bowl LV between the Tampa Bay Buccaneers and the Kansas City Chiefs at Raymond James Stadium. Mandatory Credit: Kim Klement-USA TODAY Sports /
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NFL 2022
INDIANAPOLIS, INDIANA – JANUARY 02: Jonathan Taylor #28 of the Indianapolis Colts runs the ball in the game against the Las Vegas Raiders at Lucas Oil Stadium on January 02, 2022 in Indianapolis, Indiana. (Photo by Justin Casterline/Getty Images) /

46. Sunday, Sept 11. 0. 1:00 PM ET. 0. . 10.

NFL Week 1: Indianapolis Colts vs. Houston Texans

Home-field advantage is about the only advantage the Houston Texans will have in this divisional matchup.

The Indianapolis Colts, now led by quarterback Matt Ryan, have a better offense and a far better defense.

Texans sophomore quarterback Davis Mills has too tough of a task for an inexperienced signal caller with an underwhelming offensive roster.

Matt Ryan will be an upgrade for the Colts and provide more stability, leadership, and overall consistent play.

The Texans are an excellent tune-up game for Ryan to get him into a groove with his new team. Colts with the win.

Colts 31 Texans 14