2022 NFL picks, score predictions for Week 3

Los Angeles Rams (1-1) at Arizona Cardinals (1-1)

Sunday, September 25, 4:25PM ET

It’s getting hard to put too much weight behind the Los Angeles Rams right now. I know they were forced to run up against the Bills in Week 1, but they nearly choked it away against a beatable Atlanta Falcons team in Week 2. Can they really handle the Arizona Cardinals in Week 3?

I don’t think so. Matthew Stafford hasn’t been himself so far this season, and the Los Angeles defense decided not to show up after winning a Lombardi Trophy. Jalen Ramsey looks lost out there, and Aaron Donald can’t do it all on his own. Stopping Kyler Murray and Co. will be no easy feat.

Based on the magic the Cardinals’ signal caller was able to muster last weekend, I’m thinking we see more of the same against the Rams. It ends up being a close game, but that’s often the situation in which Murray thrives. Los Angeles leaves the door open, and Murray scrambles around for about 20 seconds before shimmying his way through it.

It’s another tough loss for the Rams, who appear to be suffering from a massive Super Bowl hangover. Meanwhile, the Cardinals get another quality win as they look to prove they can battle with the big boys in the NFC.

Prediction: Cardinals win 27-25