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2023 NFL picks, score predictions for Week 2

By Sayre Bedinger

Sep 10, 2023; Pittsburgh, Pennsylvania, USA; San Francisco 49ers running back Christian McCaffrey (23) runs with the ball against the Pittsburgh Steelers during the second half at Acrisure Stadium. Mandatory Credit: Gregory Fisher-USA TODAY Sports
Sep 10, 2023; Pittsburgh, Pennsylvania, USA; San Francisco 49ers running back Christian McCaffrey (23) runs with the ball against the Pittsburgh Steelers during the second half at Acrisure Stadium. Mandatory Credit: Gregory Fisher-USA TODAY Sports /
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NFL picks Week 2 /

Seattle Seahawks (0-1) @ Detroit Lions (1-0)

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