Skip to main content

2026 NFL picks, score predictions for every Week 4 game

Picks and score predictions for every Week 4 game
BySayre Bedinger
Kansas City Chiefs QB Patrick Mahomes and Las Vegas Raiders DE Maxx Crosby
Kansas City Chiefs QB Patrick Mahomes and Las Vegas Raiders DE Maxx Crosby | USA TODAY Sports via Reuters Connect
6 of 16

Arizona Cardinals (1-2) @ New York Giants (2-1)

Sunday, October 4, 1:00 PM ET

Of all the games being played in Week 4, this is one of them.

I’m kidding, I’m kidding…

We all want to see the Arizona Cardinals take on the New York Giants this weekend. Sometimes the games you least expect to be entertaining are the ones who deliver the most.

Jacoby Brissett and Jameis Winston – don’t let us down.

Actually, all kidding aside, there is quite a bit at stake for the New York Giants here in this game. The Giants are not only 2-1 this season with their only loss coming at the hands of the Los Angeles Rams, but they are 2-0 at home and have a legitimate shot against Arizona to get to 3-1.

That would not be a bad start at all for John Harbaugh in his first year with the team.

The Giants just traded for JJ McCarthy to give themselves some depth at the position and perhaps a little reclamation project to work on, but this is going to be the Jameis Winston and Cam Skattebo show. And if the Giants can get a game that isn’t affected significantly by rain, maybe they can get the passing game going a little bit.

That’s something we’ve already seen working quite well so far this season for Jacoby Brissett and the Arizona Cardinals. They have put together some nice games through the air, including throwing for 280 yards and a pair of touchdowns in an oddly competitive game against the 49ers. 

The Cardinals are surprisingly 1.5-point favorites on the road to open this week. Losing Jaxson Dart and Brian Burns in consecutive weeks has that kind of effect, but I’m still taking Harbaugh’s Giants at home.

Prediction: Giants win 19-13

Add us as a preferred source on Google

Loading recommendations... Please wait while we load personalized content recommendations