Saints vs Lions - upset alert
For a team that had a brutal season in 2025, the New Orleans Saints sure did end things off on a high note, leading some to believe that they could compete for a playoff spot this season. If that sounds familiar, that is the exact situation that the Detroit Lions found themselves in after ending the 2022 campaign on a tear and upsetting the reigning Super Bowl champion Kansas City Chiefs on banner night of the following season to put an exclamation point on Detroit being a potential contender the year the team made the NFC Championship Game. It is not the same magnitude as a defending champion, but the Saints have an opportunity to tell the world that they are a threat in 2026 and moving forward if they can upset the Lions in Detroit, which is still a respected team in the league.
Bills vs Texans - potential playoff preview
The fact of the matter is that the Buffalo Bills and Houston Texans are two really good football teams who have a track record of consistently making the playoffs in recent years. As such, this game could be a potential playoff preview. The most likely scenario for a postseason matchup between these squads would be in the Wild Card round, meaning one of these teams would have to reclaim the division title they dropped last season, and a win in this game gets that side a step closer to accomplishing that.
Cardinals vs Chargers - raise your expectations
The Arizona Cardinals going up against the Los Angeles Chargers is not going to be an all-time game, but it is one that could surprise people if they think it is going to be a one-sided affair. Before the injuries really piled on for the Cardinals last season, quarterback Jacoby Brissett led this team to a lot of close games against playoff contenders. If the Chargers take Arizona lightly and look forward to its Week 2 matchup, this game could be a fantastic one to watch, and could warrant some raised expectations for it.
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