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Week 10 NFL picks and predictions: 3 teams guaranteed to win their matchups

BySayre Bedinger
Buffalo Bills quarterback Josh Allen
Buffalo Bills quarterback Josh Allen | IMAGN IMAGES via Reuters Connect

Now that the NFL trade deadline has passed, the stage is set for the second half of the season to begin and for teams to really create separation in their respective division races.

The month of November is always pivotal, and every win is going to be crucial with the competitiveness of these races lately.

While there are absolutely no guarantees in the NFL, there are a handful of games on the schedule in Week 10 that simply feel like a foregone conclusion. The writing is on the wall, and it truly feels like there are a few teams that don't stand a chance.

Let's take a look at a handful of teams entering Week 10 action that feel like mortal locks to win their matchups.

3 NFL teams that feel guaranteed to win in Week 10 matchups

1. Jacksonville Jaguars (@ Titans)

The Jacksonville Jaguars have been playing like an absolute unit lately, winning their last two games by a combined score of 75-17.

Granted, those games came against the Colts and Ravens, but the dominance is still staggering. Now, the Jaguars have another "lesser" opponent in Week 10 in the Tennessee Titans.

Even though the Jaguars are going on the road for this one, they completely overmatch Tennessee on both sides of the ball. The ironic thing (and most "NFL" thing ever) would be for the Titans to pull off an upset after the Jaguars made all those trades to improve the roster at the deadline (Jessie Bates, Jordan Davis, Davon Godchaux), but that feels incredibly unlikely.

The Jags are favored on the road by 10.5 points, making them the biggest favorite of the week. I'm guessing they will once again take care of business against a struggling team and coast to their 7th win of the season.

2. Buffalo Bills (@ Jets)

Another AFC powerhouse that feels all but guaranteed to win this weekend is the Buffalo Bills.

The Bills are coming off a very important win on the road against the Minnesota Vikings. It wasn't a mission-critical AFC win, but it was an important litmus test for the Bills. Even going against a struggling Vikings offense, the Bills showed that they are one of the most well-rounded teams in the NFL, and fully capable of moving the ball even against one of the league's most feared defenses.

Now, they get a chance to go on the road to face the Jets. The Jets have given up 26+ points in four straight games, and they've given up 73 points over the last two games combined.

The Bills should be able to move the ball and score at will against the Jets. You can never overlook a divisional opponent, but the Bills are 8.5-point favorites in this one and could be the third team in a row to face the Jets and put up 35 or more points.

3. Los Angeles Rams (@ Cardinals)

The Los Angeles Rams have struggled to a 5-4 record this season, but they are 3-1 on the road so far. They've already lost one game to the Arizona Cardinals this year, and they're not going to lose another one.

This game got another jolt of intrigue when it was announced that rookie quarterback Carson Beck would be taking over for the injured Gardner Minshew.

Beck will be making his NFL starting debut on the same week as #1 overall pick Fernando Mendoza, so this is an exciting weekend for the league.

But for the Cardinals? It's going to be a rough matchup having a rookie quarterback going up against Myles Garrett, who had 3 sacks in his return to the field last week. Even with all of the injuries the Rams have been/are dealing with this season, they are justifiably 9.5-point road favorites in this matchup.

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