DraftKings NFL Picks, Week 10: Best bargains in DFS play

NEW ORLEANS, LOUISIANA - OCTOBER 27: Kyler Murray #1 of the Arizona Cardinals looks to pass against the New Orleans Saints in their NFL game at Mercedes Benz Superdome on October 27, 2019 in New Orleans, Louisiana. (Photo by Chris Graythen/Getty Images)
NEW ORLEANS, LOUISIANA - OCTOBER 27: Kyler Murray #1 of the Arizona Cardinals looks to pass against the New Orleans Saints in their NFL game at Mercedes Benz Superdome on October 27, 2019 in New Orleans, Louisiana. (Photo by Chris Graythen/Getty Images) /
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INDIANAPOLIS, IN – OCTOBER 27: Marlon Mack #25 of the Indianapolis Colts runs into the end zone for a touchdown in the third quarter of the game against the Denver Broncos at Lucas Oil Stadium on October 27, 2019 in Indianapolis, Indiana. (Photo by Bobby Ellis/Getty Images)
INDIANAPOLIS, IN – OCTOBER 27: Marlon Mack #25 of the Indianapolis Colts runs into the end zone for a touchdown in the third quarter of the game against the Denver Broncos at Lucas Oil Stadium on October 27, 2019 in Indianapolis, Indiana. (Photo by Bobby Ellis/Getty Images) /

Running Backs

Marlon Mack (IND vs. MIA, $7000): Anyone that requires prompting to start Mack against a Miami Dolphins defense ranked dead last against running backs needs a pulse check. Expect Mack to play an even larger role in the offense with starting quarterback Jacoby Brissett sidelined.

Derrick Henry (TEN vs. KC, $6,400):  Going into this week, Henry was the ninth-ranked running back in PPR formats. While he’s somewhat game script dependent, his floor as the unchallenged red zone back is high enough against a Chiefs defense ranked 29th in the league in terms of fantasy points allowed to running backs.

More from NFL Spin Zone

With Matt Breida questionable and George Kittle unlikely to play, Tevin Coleman (SF vs. SEA, $5,600) is an excellent value against a Seahawks defense that has ranked 22nd in the league in rushing yards allowed over the last three weeks. Mix in the return of both starting tackles, Joe Staley and Mike McGlinchey, and the recipe should yield well over 100 yards and a touchdown or two for Coleman.

David Montgomery (CHI vs DET, $5,300): Even Matt Nagy has discovered that feeding Montgomery gives the Chicago Bears the best chance to win. Meanwhile, the Detroit Lions are toothless against the run; only three teams allow more rushing yards per game on the ground in away games.

Devin Singletary (BUF at CLE, $5,000): The changing of the guard is official: for the second straight week, Singletary out-snapped and outperformed his teammate, Frank Gore. Expect the rookie out of Florida Atlantic to run wild against one of the three worst run defenses in the NFL.

Ronald Jones (TB vs ARI, $4,300): Jones played more than 50 percent of his team’s offensive snaps for the first time last week, racking up 82 total yards and a touchdown. Expect him to build on those numbers against an Arizona Cardinals run defense that ranks in the league’s bottom third.