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2023 NFL picks, score predictions for Week 2

By Sayre Bedinger

Sep 10, 2023; Pittsburgh, Pennsylvania, USA; San Francisco 49ers running back Christian McCaffrey (23) runs with the ball against the Pittsburgh Steelers during the second half at Acrisure Stadium. Mandatory Credit: Gregory Fisher-USA TODAY Sports
Sep 10, 2023; Pittsburgh, Pennsylvania, USA; San Francisco 49ers running back Christian McCaffrey (23) runs with the ball against the Pittsburgh Steelers during the second half at Acrisure Stadium. Mandatory Credit: Gregory Fisher-USA TODAY Sports /
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The opening week of the 2023 NFL season did not disappoint. Although there were some low-scoring games and not the greatest offensive performances league-wide, the NFL is back and it was an exciting first week of action, even for NFL picks and predictions.

2023 NFL picks and score predictions for Week 2

NFL picks
NFL picks – Mandatory Credit: Brian Fluharty-USA TODAY Sports /

Minnesota Vikings (0-1) @ Philadelphia Eagles (1-0)

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